FoodSafe™ – IgG4
FoodSafe™ IgG4 measures IgG4 antibodies directed against specific foods. IgG4 is a subclass of IgG that often develops gradually with ongoing exposure to the same foods over time.
IgE is associated with immediate allergic reactions, while IgG4 is linked to longer-term immune exposure and adaptation.
The test highlights foods that consistently engage the immune system and can support elimination or rotation diet planning.
Results are reported as relative IgG4 levels with population percentile context. Percentiles describe statistical distribution only and do not predict symptoms or disease.
No. This test does not diagnose food allergies or intolerances.
Results are intended to support informed dietary discussions with a healthcare provider.
IgG4 focuses on a single immune pathway, while Total IgG offers a broader overview.
Yes. IgG4 levels may change with dietary modifications.
A small capillary blood sample (~400 µL whole blood) is collected using a micro-collection device.
FoodSafe™ – Total IgG
It measures combined IgG antibodies (IgG1, IgG2, IgG3, and IgG4) against specific foods.
Total IgG captures broad immune recognition, while IgG4 focuses on long-term exposure patterns.
It identifies foods frequently recognized by the immune system, reflecting dietary exposure.
Results are shown as relative IgG levels with population percentile context. Percentiles describe how common a response is.
No. It does not assess IgE-mediated allergy.
Results support dietary awareness and planning with a healthcare provider.
Total IgG provides a wide-angle view, while IgG4 offers a focused lens.
Yes. Levels may change with diet and exposure frequency.
A small capillary blood sample (~200 µL serum) is collected using a micro-collection device.
Inhalant Allergen – IgE
This test measures specific IgE antibodies in your blood that react to common airborne allergens such as pollens, molds, animal dander, and dust mites. Elevated IgE levels indicate that your immune system recognizes these substances as allergens.
IgE stands for Immunoglobulin E, a type of antibody produced by the immune system. It plays a key role in allergic reactions by binding to allergens and triggering the release of histamine and other inflammatory chemicals.
The panel screens for a wide range of inhalant allergens grouped into several categories:
- Animals: Cat, dog, and dust mites
- Grasses: Bahia, Kentucky blue (meadow), Timothy, Sweet Vernal
- Molds: Alternaria, Aspergillus, Candida, Cladosporium
- Trees: Ash, birch, cedar, cottonwood, elm, maple, oak, pecan, walnut
- Weeds: Cocklebur, ragweed, lamb’s quarter, mugwort, pigweed, plantain, thistle
(See your report for the specific results for each allergen.)
Your inhalant allergy results are reported in kU/L (kilounits per liter). This number reflects the amount of IgE antibodies in your blood that are specific to a particular environmental trigger—such as pollen, mold, dust mites, or animal dander.
Higher values indicate stronger immune recognition of that substance. However, the number alone does not determine whether you will experience symptoms.
In addition to your kU/L value, your report shows how your results compare to the general population, using percentile markers.
A percentile shows how your result ranks compared to others:
- 80th percentile – Higher than about 80% of people tested
- 95th percentile – Higher than about 95% of people tested
- 97th percentile – Higher than about 97% of people tested
- 99.5th percentile – Higher than about 99.5% of people tested
These markers help place your result in real-world context, rather than viewing the number in isolation.
- Below the 80th percentile
Common in the general population. Often reflects low or minimal immune recognition. - 80th–95th percentile
Higher-than-average immune awareness. Some individuals may notice mild or situational symptoms. - 95th–97th percentile
Strong immune sensitivity compared to most people. More commonly associated with noticeable reactions. - Above the 97th or 99.5th percentile
Very high immune recognition. These levels are uncommon in the general population and may be more likely to correlate with symptoms when exposure occurs.
Importantly, percentiles do not diagnose allergies. Some people with high IgE levels have few symptoms, while others with lower levels may be more sensitive.
Using both measurements provides a clearer picture:
- kU/L shows the absolute level of allergen-specific IgE
- Percentiles show how unusual or common that level is among other people
Together, they help you and your healthcare provider better understand whether a result represents:
- Typical background exposure
- Elevated sensitivity
- Unusually high immune reactivity
Not necessarily.
This test measures immune recognition, not symptoms or disease. Environmental IgE results should always be considered alongside:
- Your symptoms (if any)
- Timing and seasonality
- Exposure history
- Clinical judgment
For questions about diagnosis or treatment, results should be reviewed with a qualified healthcare professional.
Understanding how your immune system responds to common environmental exposures can:
- Provide insight into possible symptom triggers
- Help explain seasonal or environment-related discomfort
- Support informed conversations with your healthcare provider
This information is intended for educational and wellness awareness purposes, not as a stand-alone diagnostic tool.
Total IgE reflects the overall allergic antibody load in your system. Elevated levels may suggest a generalized allergic tendency, though some people with high IgE have few symptoms and vice versa. Your provider will interpret this result in context with your history and other findings.
Not always. A positive IgE test confirms sensitization but not necessarily symptomatic allergy. Clinical correlation, based on exposure history and symptom patterns, is essential before making treatment or avoidance decisions.
The test was performed on the Siemens Noveos™ automated immunoassay platform in a CLIA-certified Meridian Valley Laboratory (CLIA #50D0630590).
Note: This laboratory-developed test has not been cleared or approved by the U.S. FDA, but its analytical performance has been validated for clinical use.
The Noveos™ Inhalant Allergen IgE Profile requires approximately 400 µL of serum, typically obtained from:
- Venous blood draw (standard collection at a clinic or laboratory)
- Capillary blood collection (finger stick or upper-arm micro-collection device such as a Tasso-type device, often called a microsampler or remote capillary collection device)
Serum is separated from whole blood and used for IgE measurement.
Discuss the results with your healthcare provider. Together you can identify which allergens are most relevant based on your environment and symptoms. Strategies may include:
- Environmental control measures (air filters, bedding encasements, pet avoidance)
- Targeted immunotherapy (allergy shots or sublingual drops)
- Medications to reduce allergic inflammation
No fasting or medication restriction is typically required. However, total IgE and specific IgE levels can change with treatment, environment, or season, so repeat testing should be timed and interpreted accordingly.
Yes. Comparing IgE levels over time can help track the immune response to immunotherapy or environmental interventions, though symptom improvement remains the most important indicator of clinical progress.
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